张雅超  研究员  

研究方向:

电子邮件:zhangyachao@sibet.ac.cn

电       话:0086-0512-69588221

通讯地址:苏州市高新区科技城科灵路88号

 

简       历:

张雅超,研究员,中国科学技术大学博士生导师。202010月毕业于香港城市大学机械与生物医学工程系,获得博士学位。2020-2022年期间先后在香港城市大学、香港理工大学任博士后研究员。20231月加入中国科学院苏州生物医学工程技术研究所 (中科院高层次引才计划择优通过)。长期以来从事超声成像和光声成像前沿技术研究和应用研究, 研究领域涵盖从方法学、仪器装备到应用场景,取得了一系列重要的原创性成果。近5年,主持项目包括国家重点研发计划课题,中国科学院高层次引才计划项目,姑苏青年创新领军人才项目,国自然基金项目等。发表领域内高水平学术会议论文超过30篇,包括Science AdvancesAdvanced ScienceIEEE TMIPhotoacousticsPhotonics ResearchAdvanced PhotonicsBiomedical Optics ExpressAdvanced MaterialsAngew. Chem. In. Ed.等,其中第一作者、共同一作和通讯作者论文18 (含中科院一区11)。申请美国发明专利2项,中国发明专利2项。目前担任中国仪器仪表学会显微仪器分会委员, 中国生物医学工程学会高级会员。同时长期担任IEEE TMIPhotoacousticsApplied OpticsMedical Physics10余个国际主流期刊的审稿人。

获奖及荣誉:

1. 中国智能制造十大科技进展奖 (2019)

2. 香港城市大学杰出学术表现奖 (2019)

3. 瑞士日内瓦国际发明奖 (2021)

4. 香港医疗及保健器材行业协会研究奖 (2022)

5. 中科院高层次引才计划(择优通过2022)

6. 第二届生物医学光子学交叉融合学术论坛优秀报告奖和最佳人气奖 (2023)

7. 姑苏青年创新领军人才 (2023)

 

社会任职:

1. 中国仪器仪表学会显微仪器分会 委员

2. 中国生物医学工程学会 高级会员

研究方向:

涵盖成像新方法、核心部件、仪器装备、应用场景:

1. 光声成像

2. 超声成像

3. 超声/光学多模态成像

4. 全脑超分辨在体功能成像

5. 超快心肌微循环成像

承担项目情况:

主持项目(20232-至今)

1. 国家重点研发计划 “基础科研条件与重大科学仪器设备研发”重点专项 (课题1),超分辨率光声成像分析仪,2023.12-2026.11

2. 国家自然科学基金项目,面向临床组织异质性矫正的深层超声/光声多模态成像,2024.01-2026.12

3. 中科院高层次引才计划项目(人才项目)2023.02-2026.01

4. 姑苏青年创新领军人才项目(人才项目)2023.07-2026.06

代表论著:

1.Zhang Y, Chen J, Zhang J, et al. SuperLowDose Functional and Molecular Photoacoustic Microscopy[J]. Advanced Science (领域顶刊), 2022: 2302486.

2. [Liu G, Zhang Y], Yao H, et al. An ultrasound-activatable platinum prodrug for sono-sensitized chemotherapy[J]. Science Advances (共同一作, 领域顶刊), 2023, 9(25): eadg5964.

3. Zhang Y, Wang L. Video-rate ring-array ultrasound and photoacoustic tomography[J]. IEEE Transactions on Medical Imaging, 2020, 39(12): 4369-4375. (领域顶刊).

4. Zhang Y, Yue Wang, Puxiang Lai, Wang L. Video-rate Dual-modal Wide-beam Harmonic Ultrasound and Photoacoustic Computed Tomography [J]. IEEE Transactions on Medical Imaging, 2022, 41(3): 727-736. (领域顶刊).

5. Zhang Y, Wang L. Adaptive dual-speed ultrasound and photoacoustic computed tomography[J]. Photoacoustics, 2022, 27: 100380. (领域顶刊).

6. Yachao Zhang, Lidai Wang. Video-rate full-ring ultrasound and photoacoustic computed tomography with real-time sound speed optimization. Biomedical Optics Express, 2022, 13(8), 4398-4413. (中科院二区).

7. Zhang Y, Wang L. Array-based high-intensity focused ultrasound therapy system integrated with real-time ultrasound and photoacoustic imaging[J]. Biomedical Optics Express, 2023, 14(3): 1137-1145. (中科院二区,入选期刊亮点推荐文章).

8. Zhang, Yachao, and Lidai Wang. "Speed of Sound Self-compensated Video-rate Full-ring Ultrasound and Photoacoustic Computed Tomography." IEEE Region 10 Conference (TENCON). IEEE, 2022. (会议论文)

9. Yachao Zhang, Yue Wang, Puxiang Lai, Lidai Wang. Linear array-based video-rate wide-beam harmonic ultrasound and single-shot photoacoustic computed tomography. ICBHI2021. (会议论文)

10. Shuo Qi, Jiangbo Chen, Peng Cao, Xiaohua Lei, Chengming Ding, Guodong Chen,Yachao Zhang*, Lidai Wang. Targeted Multifunctional Nanoplatform for Imaging-Guided Precision Diagnosis and Photothermal/ Photodynamic Therapy of Orthotopic Hepatocellular Carcinoma. International Journal of Nanomedicine, 2022: 3777-3792. (通讯作者,领域顶刊).

11. [Chen J, Zhang Y*], He L, et al. Wide-field polygon-scanning photoacoustic microscopy of oxygen saturation at 1-MHz A-line rate. Photoacoustics, 2020, 20: 100195. (共同一作, 领域顶刊).

12. [CHEN J, ZHANG Y*, LI X], et al. Confocal Visible/NIR Photoacoustic Microscopy of Tumor with Structural, Functional, and Nanoprobe Contrasts[J]. Photonics Research, 2020, 8(12): 1875-1880. (共同一作, 领域顶刊).

13. [Jie Zhang, Yachao Zhang*], Multispectral Fluorescent and Photoacoustic Dual-Modal Probe for Simultaneous Detection and Discrimination of Biothiols in cells and mice. ACS Sensors, 2022, 7(4): 1105-1112. (共同一作,领域顶刊).

14. [Qi Shuo, Yachao Zhang*, Liu Gongyuan], et al. Plasmonic-Doped Melanin-Mimic for CXCR4-Targeted NIR-II Photoacoustic Computed Tomography-Guided Photothermal Ablation of Orthotopic Hepatocellular Carcinoma. Acta Biomaterialia, 2021, 129: 245-257. (共同一作,领域顶刊).

15. [He Linyun, Yachao Zhang*, Jiangbo Chen], et al. A multifunctional targeted nanoprobe with high NIR-II PAI/MRI performance for precise theranostics of orthotopic early-stage hepatocellular carcinoma. Journal of Materials Chemistry B, 2021, 9(42): 8779-8792. (共同一作,中科院二区,封面文章).

16. [Wen G, Li X, Zhang Y*], et al.  Effective Phototheranostics of Brain Tumor Assisted by Near-Infrared-II Light-Responsive Semiconducting Polymer Nanoparticles[J]. ACS Applied Materials & Interfaces, 2020, 12(30): 33492-33499. (共同一作,领域顶刊).

17. [Li S, Deng Q, Zhang Y*], et al. Rational Design of Conjugated Small Molecules for Superior Photothermal Theranostics in the NIR-II Biowindow[J]. Advanced Materials, 2020, 32(33): 2001146. (共同一作,领域顶刊).

18. [Li D, Zhang Y, Liu C], et al. Review of photoacoustic imaging for microrobots tracking in vivo[J]. Chinese Optics Letters, 2021, 19(11): 111701. (共同一作受邀文章封面文章).

19. Wang W, Zhang Y, Zhang Y, et al. Biomimetic liposomes as a pH/ROS cascade-responsive nanoagent with high selectivity for breast carcinoma in photothermal therapy[J]. Materials & Design, 2023, 234: 112304. (领域顶刊).

20. Hakakzadeh S, Amjadian M, Zhang Y, et al. Signal restoration algorithm for photoacoustic imaging systems[J]. Biomedical Optics Express, 2023, 14(2): 651-666. (中科院二区).

21. Qu, Z., Liu, C., Zhu, J., Zhang, Y., Zhou, Y., & Wang, L. (2022). Two-step proximal gradient descent algorithm for photoacoustic signal unmixing. Photoacoustics27, 100379. (领域顶刊).

22. Zhu, J., Liu, C., Liu, Y., Chen, J., Zhang, Y., Yao, K., & Wang, L. Self-fluence-compensated functional photoacoustic microscopy. IEEE Transactions on Medical Imaging, 2021, 40(12): 3856-3866. (领域顶刊).

23. Chen J, Zhang Y, Zhu J, et al. Freehand scanning photoacoustic microscopy with simultaneous localization and mapping[J]. Photoacoustics, 2022: 100411. (领域顶刊).

24. Chen J, Zhang Y, Bai S, et al. Dual-foci fast-scanning photoacoustic microscopy with 3.2-MHz A-line rate[J]. Photoacoustics, 2021, 23: 100292. (领域顶刊).

25. Chao Liu, Jiangbo Chen, Yachao Zhang, et al. Five-Wavelength Optical-Resolution Photoacoustic Microscopy of Blood and Lymphatic Vessels. Advanced Photonics, 2021, 3(1): 016002. (领域顶刊).

26. Zha, M., Lin, X., Ni, J. S., Li, Y., Zhang, Y., Zhang, X., ... & Li, K. An Ester-substityted Semiconducting Polymer with Efficient Nonradiative Decay Enhances NIR-II Photoacoustic Performance for Monitoring of Tumor Grouth. Angewandte Chemie International Edition, 2021, 40(12): 3856-3866.(领域顶刊).

27. Wei, T., Liu, J., Li, D., Chen, S., Zhang, Y., Li, J., ... & Sun, D. Development of Magnet-Driven and Image-Guided Degradable Microrobots for the Precise Delivery of Engineered Stem Cells for Cancer Therapy. Small, 2020, 16(41): 1906908. (领域顶刊).

28. Yin, C., Li, X., Wen, G., Yang, B., Zhang, Y., Chen, X., ... & Lee, C. S. Organic semiconducting polymer amphiphile for near-infrared-II light-triggered phototheranostics. Biomaterials, 2020, 232: 119684. (领域顶刊).

29. Zhu, J., Chen, J., Amjadian, M., Liang, S., Qu, Z., Wang, Y., Zhang, Y., Wang, L. (2023). Simultaneous dual-modal photoacoustic and harmonic ultrasound microscopy with an optimized acoustic combiner. Biomedical Optics Express14(4), 1626-1635. (中科院二区).

 

详情请参考RGGoogle Scholar

RG

https://www.researchgate.net/profile/Yachao-Zhang-6

Google Scholar

https://scholar.google.com.hk/citations?hl=zh-CN&user=zT3PRQUAAAAJ#d=gs_hdr_drw&t=1688701905989

 

发明专利:

1.WANG, Lidai; ZHANG, Yachao; System and Method for Photoacoustic Imaging and Ultrasound Imaging. 美国发明专利, 申请号:17/879,264, 日期:2022.08.02.

2.SUN, Dong; WEI, Tanyong; WANG, Lidai; LI, Dongfang; ZHANG, Yachao; CHEN, Shuxun. Magnetically-drivable Microrobot. 美国发明专利, US Patent 11,826,955, 授权日期:2023.11.28.

3.孙东; 魏坦勇; 王立代; 李东方; 张雅超; 陈书勋; 可磁驱动的微型机器人及制造方法. 中国发明专利, 申请号:CN202110817860.4, 日期:2022.01.25.

4.谭庆昌; 包昊菁; 刘思远; 张雅超; 原敏乔; 周晓东; 基于机器视觉系统的指针式仪表读数识别测量方法. 中国发明专利, 申请号:CN201710532391.5, 日期:2019.04.26