张雅超,研究员,中国科学技术大学博士生导师。2020年10月毕业于香港城市大学机械与生物医学工程系,获得博士学位。2020-2022年期间先后在香港城市大学、香港理工大学任博士后研究员。2023年1月加入中国科学院苏州生物医学工程技术研究所 (中科院高层次引才计划择优通过)。长期以来从事超声成像和光声成像前沿技术研究和应用研究, 研究领域涵盖从方法学、仪器装备到应用场景,取得了一系列重要的原创性成果。近5年,主持项目包括国家重点研发计划课题,中国科学院高层次引才计划项目,姑苏青年创新领军人才项目,国自然基金项目等。发表领域内高水平学术会议论文超过30篇,包括Science Advances,Advanced Science,IEEE TMI,Photoacoustics,Photonics Research,Advanced Photonics,Biomedical Optics Express,Advanced Materials,Angew. Chem. In. Ed.等,其中第一作者、共同一作和通讯作者论文18篇 (含中科院一区11篇)。申请美国发明专利2项,中国发明专利2项。目前担任中国仪器仪表学会显微仪器分会委员, 中国生物医学工程学会高级会员。同时长期担任IEEE TMI,Photoacoustics,Applied Optics,Medical Physics等10余个国际主流期刊的审稿人。
1. 中国智能制造十大科技进展奖 (2019)
2. 香港城市大学杰出学术表现奖 (2019)
3. 瑞士日内瓦国际发明奖 (2021)
4. 香港医疗及保健器材行业协会研究奖 (2022)
5. 中科院高层次引才计划(择优通过,2022)
6. 第二届生物医学光子学交叉融合学术论坛优秀报告奖和最佳人气奖 (2023)
7. 姑苏青年创新领军人才 (2023)
1. 中国仪器仪表学会显微仪器分会 委员
2. 中国生物医学工程学会 高级会员
涵盖成像新方法、核心部件、仪器装备、应用场景:
1. 光声成像
2. 超声成像
3. 超声/光学多模态成像
4. 全脑超分辨在体功能成像
5. 超快心肌微循环成像
主持项目(2023年2月-至今):
1. 国家重点研发计划 “基础科研条件与重大科学仪器设备研发”重点专项 (课题1),超分辨率光声成像分析仪,2023.12-2026.11。
2. 国家自然科学基金项目,面向临床组织异质性矫正的深层超声/光声多模态成像,2024.01-2026.12。
3. 中科院高层次引才计划项目(人才项目),2023.02-2026.01。
4. 姑苏青年创新领军人才项目(人才项目),2023.07-2026.06。
1.Zhang Y, Chen J, Zhang J, et al. Super‐Low‐Dose Functional and Molecular Photoacoustic Microscopy[J]. Advanced Science (领域顶刊), 2022: 2302486.
2. [Liu G, Zhang Y], Yao H, et al. An ultrasound-activatable platinum prodrug for sono-sensitized chemotherapy[J]. Science Advances (共同一作, 领域顶刊), 2023, 9(25): eadg5964.
3. Zhang Y, Wang L. Video-rate ring-array ultrasound and photoacoustic tomography[J]. IEEE Transactions on Medical Imaging, 2020, 39(12): 4369-4375. (领域顶刊).
4. Zhang Y, Yue Wang, Puxiang Lai, Wang L. Video-rate Dual-modal Wide-beam Harmonic Ultrasound and Photoacoustic Computed Tomography [J]. IEEE Transactions on Medical Imaging, 2022, 41(3): 727-736. (领域顶刊).
5. Zhang Y, Wang L. Adaptive dual-speed ultrasound and photoacoustic computed tomography[J]. Photoacoustics, 2022, 27: 100380. (领域顶刊).
6. Yachao Zhang, Lidai Wang. Video-rate full-ring ultrasound and photoacoustic computed tomography with real-time sound speed optimization. Biomedical Optics Express, 2022, 13(8), 4398-4413. (中科院二区).
7. Zhang Y, Wang L. Array-based high-intensity focused ultrasound therapy system integrated with real-time ultrasound and photoacoustic imaging[J]. Biomedical Optics Express, 2023, 14(3): 1137-1145. (中科院二区,入选期刊亮点推荐文章).
8. Zhang, Yachao, and Lidai Wang. "Speed of Sound Self-compensated Video-rate Full-ring Ultrasound and Photoacoustic Computed Tomography." IEEE Region 10 Conference (TENCON). IEEE, 2022. (会议论文)
9. Yachao Zhang, Yue Wang, Puxiang Lai, Lidai Wang. Linear array-based video-rate wide-beam harmonic ultrasound and single-shot photoacoustic computed tomography. ICBHI2021. (会议论文)
10. Shuo Qi, Jiangbo Chen, Peng Cao, Xiaohua Lei, Chengming Ding, Guodong Chen,Yachao Zhang*, Lidai Wang. Targeted Multifunctional Nanoplatform for Imaging-Guided Precision Diagnosis and Photothermal/ Photodynamic Therapy of Orthotopic Hepatocellular Carcinoma. International Journal of Nanomedicine, 2022: 3777-3792. (通讯作者,领域顶刊).
11. [Chen J, Zhang Y*], He L, et al. Wide-field polygon-scanning photoacoustic microscopy of oxygen saturation at 1-MHz A-line rate. Photoacoustics, 2020, 20: 100195. (共同一作, 领域顶刊).
12. [CHEN J, ZHANG Y*, LI X], et al. Confocal Visible/NIR Photoacoustic Microscopy of Tumor with Structural, Functional, and Nanoprobe Contrasts[J]. Photonics Research, 2020, 8(12): 1875-1880. (共同一作, 领域顶刊).
13. [Jie Zhang, Yachao Zhang*], Multispectral Fluorescent and Photoacoustic Dual-Modal Probe for Simultaneous Detection and Discrimination of Biothiols in cells and mice. ACS Sensors, 2022, 7(4): 1105-1112. (共同一作,领域顶刊).
14. [Qi Shuo, Yachao Zhang*, Liu Gongyuan], et al. Plasmonic-Doped Melanin-Mimic for CXCR4-Targeted NIR-II Photoacoustic Computed Tomography-Guided Photothermal Ablation of Orthotopic Hepatocellular Carcinoma. Acta Biomaterialia, 2021, 129: 245-257. (共同一作,领域顶刊).
15. [He Linyun, Yachao Zhang*, Jiangbo Chen], et al. A multifunctional targeted nanoprobe with high NIR-II PAI/MRI performance for precise theranostics of orthotopic early-stage hepatocellular carcinoma. Journal of Materials Chemistry B, 2021, 9(42): 8779-8792. (共同一作,中科院二区,封面文章).
16. [Wen G, Li X, Zhang Y*], et al. Effective Phototheranostics of Brain Tumor Assisted by Near-Infrared-II Light-Responsive Semiconducting Polymer Nanoparticles[J]. ACS Applied Materials & Interfaces, 2020, 12(30): 33492-33499. (共同一作,领域顶刊).
17. [Li S, Deng Q, Zhang Y*], et al. Rational Design of Conjugated Small Molecules for Superior Photothermal Theranostics in the NIR-II Biowindow[J]. Advanced Materials, 2020, 32(33): 2001146. (共同一作,领域顶刊).
18. [Li D, Zhang Y, Liu C], et al. Review of photoacoustic imaging for microrobots tracking in vivo[J]. Chinese Optics Letters, 2021, 19(11): 111701. (共同一作,受邀文章,封面文章).
19. Wang W, Zhang Y, Zhang Y, et al. Biomimetic liposomes as a pH/ROS cascade-responsive nanoagent with high selectivity for breast carcinoma in photothermal therapy[J]. Materials & Design, 2023, 234: 112304. (领域顶刊).
20. Hakakzadeh S, Amjadian M, Zhang Y, et al. Signal restoration algorithm for photoacoustic imaging systems[J]. Biomedical Optics Express, 2023, 14(2): 651-666. (中科院二区).
21. Qu, Z., Liu, C., Zhu, J., Zhang, Y., Zhou, Y., & Wang, L. (2022). Two-step proximal gradient descent algorithm for photoacoustic signal unmixing. Photoacoustics, 27, 100379. (领域顶刊).
22. Zhu, J., Liu, C., Liu, Y., Chen, J., Zhang, Y., Yao, K., & Wang, L. Self-fluence-compensated functional photoacoustic microscopy. IEEE Transactions on Medical Imaging, 2021, 40(12): 3856-3866. (领域顶刊).
23. Chen J, Zhang Y, Zhu J, et al. Freehand scanning photoacoustic microscopy with simultaneous localization and mapping[J]. Photoacoustics, 2022: 100411. (领域顶刊).
24. Chen J, Zhang Y, Bai S, et al. Dual-foci fast-scanning photoacoustic microscopy with 3.2-MHz A-line rate[J]. Photoacoustics, 2021, 23: 100292. (领域顶刊).
25. Chao Liu, Jiangbo Chen, Yachao Zhang, et al. Five-Wavelength Optical-Resolution Photoacoustic Microscopy of Blood and Lymphatic Vessels. Advanced Photonics, 2021, 3(1): 016002. (领域顶刊).
26. Zha, M., Lin, X., Ni, J. S., Li, Y., Zhang, Y., Zhang, X., ... & Li, K. An Ester-substityted Semiconducting Polymer with Efficient Nonradiative Decay Enhances NIR-II Photoacoustic Performance for Monitoring of Tumor Grouth. Angewandte Chemie International Edition, 2021, 40(12): 3856-3866.(领域顶刊).
27. Wei, T., Liu, J., Li, D., Chen, S., Zhang, Y., Li, J., ... & Sun, D. Development of Magnet-Driven and Image-Guided Degradable Microrobots for the Precise Delivery of Engineered Stem Cells for Cancer Therapy. Small, 2020, 16(41): 1906908. (领域顶刊).
28. Yin, C., Li, X., Wen, G., Yang, B., Zhang, Y., Chen, X., ... & Lee, C. S. Organic semiconducting polymer amphiphile for near-infrared-II light-triggered phototheranostics. Biomaterials, 2020, 232: 119684. (领域顶刊).
29. Zhu, J., Chen, J., Amjadian, M., Liang, S., Qu, Z., Wang, Y., Zhang, Y., Wang, L. (2023). Simultaneous dual-modal photoacoustic and harmonic ultrasound microscopy with an optimized acoustic combiner. Biomedical Optics Express, 14(4), 1626-1635. (中科院二区).
详情请参考RG或Google Scholar:
RG:
https://www.researchgate.net/profile/Yachao-Zhang-6
Google Scholar:
https://scholar.google.com.hk/citations?hl=zh-CN&user=zT3PRQUAAAAJ#d=gs_hdr_drw&t=1688701905989
发明专利:
1.WANG, Lidai; ZHANG, Yachao; System and Method for Photoacoustic Imaging and Ultrasound Imaging. 美国发明专利, 申请号:17/879,264, 日期:2022.08.02.
2.SUN, Dong; WEI, Tanyong; WANG, Lidai; LI, Dongfang; ZHANG, Yachao; CHEN, Shuxun. Magnetically-drivable Microrobot. 美国发明专利, US Patent 11,826,955, 授权日期:2023.11.28.
3.孙东; 魏坦勇; 王立代; 李东方; 张雅超; 陈书勋; 可磁驱动的微型机器人及制造方法. 中国发明专利, 申请号:CN202110817860.4, 日期:2022.01.25.
4.谭庆昌; 包昊菁; 刘思远; 张雅超; 原敏乔; 周晓东; 基于机器视觉系统的指针式仪表读数识别测量方法. 中国发明专利, 申请号:CN201710532391.5, 日期:2019.04.26
张雅超 研究员
研究方向:
电子邮件:zhangyachao@sibet.ac.cn
电 话:0086-0512-69588221
通讯地址:苏州市高新区科技城科灵路88号