现任中国科学院苏州生物医学工程技术研究所研究员，中国科学院特聘骨干，中国科学技术大学教授、博士生导师。现担任中国科学院青年创新促进会理事、工程装备分会委员，中国生物医学工程学会医学测量分会委员，中国医疗器械行业协会现场快检与智慧家测专委会委员，中国心胸血管与麻醉学会检验与临床分会常务委员，江苏省免疫学会感染免疫专业委员会委员，苏州中西医结合分会检验专业委员会常务委员，全国纳米技术标准化技术委员会苏州工作组（SAC/TC279/WG11）委员。作为项目/课题负责人承担科技部重点研发计划2项、国自然基金、国家重大科研仪器研制项目、江苏省重点项目等多项。发表SCI/EI论文40余篇，申请专利60余项，其中发明专利授权25项，美国专利授权1项。入选中国科学院青年创新促进会优秀会员，江苏省双创团队，江苏省333高层次人才等。
1. 生物医学传感、生物化学
2. 肿瘤液体活检技术
3. 单细胞检测与分析
代表论著：
1. Hao Li, Jinze Li, Zhiqi Zhang, Qi Yang, Hong Du, Qiongzhu Dong, Zhen Guo, Jia Yao, Shuli Li, Dongshu Li, Nannan Pang, Chuanyu Li,* Wei Zhang*, and Lianqun Zhou*, Digital Quantitative Detection for Heterogeneous Protein and mRNA Expression Patterns in Circulating Tumor Cells, Advanced Science, 2025, 2410120. （通讯作者）
2. Mingli Tao, Qi Yang, Changxiang Huan, Zhiqi Zhang, Peilong Li, Runhu Huang, Juan Li, Yueye Zhang, Chao Li, Chuanyu Li, Jia Yao, Shuli Li, Zhen Guo, Wei Zhang*, Jinze Li*, Lianqun Zhou*, Multiplex methylation detection assays using a blocking FRET probe with machine learning-assisted quantitative melting curve method targeting early-stage breast cancer, Chemical Engineering Journal, 2024, 498:155093. (通讯作者)
3. Lu Wang, Peilin Zang, Jinze Li, Zhiqi Zhang, Chao Li, Anran Zheng, Shasha Zhao, Jia Yao, Chuanyu Li, Zhen Guo, Wei Zhang*, Lianqun Zhou*, Single Effective Complex Loading into Zero-Mode Waveguides Optimized with Fluorescence Evaluation at Quenching and Accumulation Checkpoints, ACS Applied Materials & Interfaces, 2024, 16, 25676−25685. （通讯作者）
4. Hao Li, Jinze Li, Zhiqi Zhang, Zhen Guo, Changsong Zhang, Zixu Wang, Qiuquan Guo, Chao Li, Chuanyu Li, Jia Yao, Anran Zheng, Jingyi Xu, Qingxue Gao, Wei Zhang*, Lianqun Zhou*. Integrated microdevice with the windmill-like hole array for clog-free, efficient and self-mixing enrichment of circulating tumor cells, Microsystems & Nanoengineering, 2022, 8:23.(通讯作者)
5. Jia Yao, Yuanyuan Luo, Zhiqi Zhang, Jinze Li, Chuanyu Li, Chao Li, Zhen Guo, Lirong Wang, Wei Zhang*, Heming Zhao*, Lianqun Zhou*. The development of real-time digital PCR technology using an improved data classification method, Biosensors and Bioelectronics, 2022, 199: 113873. (通讯作者)
6. Changxiang Huan, Jinze Li, Yingxue Li, Shasha Zhao, Qi Yang, Zhiqi Zhang, Chuanyu Li, Shuli Li, Zhen Guo, Jia Yao, Wei Zhang*, Lianqun Zhou*, Spatially resolved multiomics: data analysis from monoomics to multiomics，BME FRONTIERS, 2025, 6, 0084.（通讯作者）
7. Anran Zheng, Zhen Guo, Chao Li, Zhiqi Zhang, Chuanyu Li, Jia Yao, Xin Wang, Jinze Li, Shasha Zhao, Weiguo Wang*, Wei Zhang*, Lianqun Zhou*. A wide-range UAC sensor for the classification of hyperuricemia in spot samples, Talanta, 2024, 266,125102. (通讯作者)
8. Anran Zheng, Chao Li, Shengkai Xu, Zhen Guo, Chuanyu Li, Changsong Zhang, Jia Yao, Zhiqi Zhang, Jinze Li, Lutao Du, Shasha Zhao, Chuanxin Wang*, Wei Zhang*, Lianqun Zhou*. Efficient Simultaneous Detection of Metabolites Based on Electroenzymatic Assembly Strategy, BME FRONTIERS, 2023, 0027. (通讯作者)
9. Hui Kong1, Wei Zhang1, Jia Yao, Chao Li, Renfei Lu, Zhen Guo, Jinze Li, Chuanyu Li, Yingxue Li, Chiyu Zhang, Lianqun Zhou. A RT-LAMP based hydrogen ion selective electrode sensing for effective detection HIV-1 RNA with high-sensitivity, Sensors and Actuators B-Chemical, 2021, 329: 129118. (共同一作)
10.Zhang Wei*, Chen Peihua, Zhou Lianqun, Qin Zhen, Gao Keqiang, Yao Jia, Li Chuanyu, Wang Ping*. A biomimetic bioelectronic tongue: A switch for On-and Off-response of acid sensations, Biosensors and Bioelectronics, 2017, 92: 523-528.（通讯作者）
11. Yang Yuchen1, Zhang Wei1, Guo Zhen, Zhang Zhiqi, Zhu Hongnan, Yan Ruhong, Zhou Lianqun*. Stability enhanced, repeatability improved Parylene-C passivated on QCM sensor for aPTT measurement, Biosensors and Bioelectronics, 2017, 98: 41-46. （共同一作）
12. Wei Zhang, Yan Li, Qingjun Liu, Ying Xu, Hua Cai, Ping Wang*. A novel experimental research based on taste cell chips for taste transduction mechanism. Sensors and Actuators B, 2008, 131:24-28.（独立一作）
13.Qingxue Gao, Jinze Li, Wei Zhang, Zhiqi Zhang, Runhu Huang, Peilin Zang, Shuli Li, Chao Li, Jia Yao, Chuanyu Li***,Zhen Guo**, Lianqun Zhou*, a-SiC heteromorphic immersion nanocavities enabling wide-field real-time single-molecule detection, Biosensors and Bioelectronics, 2025, 270, 116962.
14. Qi Xu, Jinze Li, Zhiqi Zhang, Qi Yang, Wei Zhang, Jia Yao, Yaxin Zhang, Yueye Zhang, Zhen Guo, Chao Li, Shuli Li, Changsong Zhang, Chuanxin Wang, Lutao Du, Chuanyu Li, Lianqun Zhou. Precise determination of reaction conditions for accurate quantification in digital PCR by real-time fluorescence monitoring within microwells, Biosensors and Bioelectronics, 2024, 244, 115798.
15.Zang, Peilin; Xu, Qi; Li, Chuanyu; Tao, Mingli; Zhang, Zhiqi; Li, Jinze; Zhang, Wei; Li, Shuli; Li, Chao; Yang, Qi; Guo, Zhen; Yao, Jia; Zhou, Lianqun. Self correction of cycle threshold values by a normal distribution–based process to improve accuracy of quantification in real time digital PCR，Analytical and Bioanalytical Chemistry, 2024, 416(10): 2453-2464.
16. Yingxue Li, Qi Xu, Wei Zhang, Qi Yang, Zhen Guo, Chuanyu Li, Zhiqi Zhang, Qiongzhu Dong, Haoting Sun, Changsong Zhang, Chao Li, Jia Yao, Jinze Li, Lunxiu Qin, Lianqun Zhou. A highly-parallelized and low-sample-size chip for simultaneous detection of protein and nucleic acid biomarkers in hepatocellular carcinoma, Sensors and Actuators B: Chemical, 2023, 392, 134112.
17. Qingxue Gao, Peilin Zang, Jinze Li, Wei Zhang, Zhiqi Zhang, Chao Li, Jia Yao, Chuanyu Li, Qi Yang, Shuli Li, Zhen Guo*, Lianqun Zhou*. Revealing the Binding Events of Single Proteins on Exosomes Using Nanocavity Antennas beyond Zero-Mode Waveguides, ACS Applied Materials & Interfaces, 2023, 15, 42, 49511–49526
18. Anran Zheng, Wei Zhang, Chao Li, Zhen Guo, Chuanyu Li, Changsong Zhang, Jia Yao, Zhiqi Zhang, Jinze Li, Shasha Zhao, Lianqun Zhou. The heparinase-linked differential time method allows detection of heparin potency in whole blood with high sensitivity and dynamic range, Biosensors and Bioelectronics, 2022, 198:113856.
19. Guojun Cao, Jinze Li, Zhifang Xing, Zhiqi Zhang, Wei Zhang, Chuanyu Li, Longhui Li, Zhen Guo, Shuli Li, Xu Gao, Yanchun Ma, Lianqun Zhou, Ming Guan. Establishment of Scalable Nanoliter Digital LAMP Technology for the Quantitative Detection of Multiple Myeloproliferative Neoplasm Molecular Markers, Sensors and Actuators B-Chemical, 2021, 346: 130493.
20. Jinze Li, Yajun Qiu, Zhiqi Zhang, Chuanyu Li, Shuli Li, Wei Zhang, Zhen Guo, Jia Yao, Lianqun Zhou. Heterogeneous modification of through-hole microwell chips for ultralow cross-contamination digital polymerase chain reaction, Analyst, 2020, 145(8): 3116-3124.
21. Xu Gao, Jinze Li, Chuanyu Li, Zhiqi Zhang, Wei Zhang, Jia Yao, Ming Guan, Zhen Guo, Chao Li, Lianqun Zhou. High filling rate digital PCR through-hole array chip with double independent s-shaped flow channels. Biomicrofluidics, 2020, 14(3): 034109.
22. Nie Qi, Zhang Wei, Wang Lirong, Guo Zhen, Li Chuanyu, Yao Jia, Li Min, Wu Dongmin, Zhou Lianqun*. Sensitivity enhanced, stability improved ethanol gas sensor based on multi-wall carbon nanotubes functionalized with Pt-Pd nanoparticles, Sensors and Actuators B-Chemical, 2018, 270: 140-148.10.
23. Wei Zhang*, Peihua Chen*, Xuefeng Shen, Jia Yao, Zhen Qin, Yuguo Tang, Zhen Guo, Lianqun Zhou*, Ping Wang*. Neural networks-based biosensor on microelectrode arrays: neural connected bioactivities and neural transmission. World Congress on Biosnesors 2018, oral presentation. (国际会议邀请报告)
代表专利：
1. 张威，王璐，郭振，周连群，李金泽，姚佳，李传宇，张芷齐，李超，杨弃。一种评估零模波导孔有效载样的方法及其应用, 授权时间2023.11.28，中国发明专利, ZL202310558188.0
2. 张威，郑安然，周连群，李超，郭振，李金泽，张芷齐，李传宇，姚佳。一种用于多重检测的电化学传感器及其制备方法和应用, 中国发明专利, CN202211043145.0
3. 张威，李豪，李金泽，周连群，张芷齐，李超，李传宇，姚佳，郭振。一种循环肿瘤细胞的富集方法及其装置，中国发明专利，CN202010568268.0
4. 张威，李豪，李金泽，周连群，张芷齐，李超，李传宇，姚佳，郭振。一种循环肿瘤细胞的富集装置, 授权时间2020.6.19，实用新型专利, ZL202021158424.8
5. 张威，周连群，李传宇，姚佳。基于声光联用的分子动力学测试平台, 授权时间2018.9.14, 中国发明专利, ZL201510598385.0
6. 张威，周连群，吴一辉。基于声光联用的分子动力学检测方法, 授权时间2018.4.17, 中国发明专利, ZL201510599139.7
7. 张威，周连群，段生宝，姚佳。一种基于压电薄膜技术的核酸单基因突变检测方法, 授权时间2017.10.8, 中国发明专利, ZL201410736193.7
8. 张威，周连群，吴一辉。一种增强压电薄膜传感器性能的图形化修饰方法, 授权时间2016.8.8, 中国发明专利, ZL201310713092.3
9. 张威，周连群，李传宇，姚佳。基于声光联用的分子动力学测试平台, 授权时间2016.2.3, 中国发明专利, ZL201520728386.8
10. 李金泽，周连群，李豪，张威，李传宇，姚佳，郭振，张芷齐，李超. 一种检测循环肿瘤细胞的方法及其应用，授权时间2024.5.7，中国发明专利，ZL202210433311.1
11. 郭振，周连群，高庆学，张威，李金泽，李超，杨弃，李传宇，姚佳，李树力。一种用于单分子动力学检测的纳米光学器件，授权时间2023.9.1，中国发明专利，ZL202310906330.6
12. 李金泽，周连群，张威，郭振，张芷齐，李超，李传宇，姚佳。一种mRNA捕获序列、捕获载体的合成方法、高通量单细胞测序文库制备方法，授权时间2022.3.8，中国发明专利，ZL201911358593.8
13. 周连群，郑安然，张威，郭振，李超，李金泽。一种凝血检测芯片和电化学传感器， 授权时间2021.7.30，中国发明专利，ZL201910229840.8
14. 李传宇，郭振，张威，姚佳，周连群，李超，张芷齐. 一种柔性电子器件的制备方法及其制备装置，授权时间2025.1.3，中国，ZL202011615919.3
15. 周连群，郭振，张威，李传宇，姚佳，张芷齐，李金泽; 唐玉国. 压电传感芯片、压电传感器及其制备方法，授权时间2024.12.27，中国发明专利，ZL201811559970.X
16. 李金泽，张琴琴，周连群，郭振，李传宇，李莹雪，姚佳，张威，李超，杨弃，张芷齐. 一种基于FQ-RCA的RNA等温实时基因分型方法，授权时间2024.5.3，中国发明专利，ZL202311061603.8
17. 周连群，高庆学，郭振，张威，李金泽，李传，姚佳，李树力，李超，杨弃。一种利用单一荧光标签的DNA测序方法，授权时间2023.11.17，中国发明专利，ZL202311049377.1
18. 李金泽，周连群，李莹雪，张威，李传宇，徐绮，姚佳，张芷齐，郭振，李超. 一种同时检测蛋白和RNA的微流控芯片及试剂盒，授权时间2024.1.26，中国发明专利，ZL202211645400.9
19. Lianqun Zhou; Chuanyu Li; Jia Yao; Wei Zhang; Zhen Guo ; NUCLEIC ACID DETECTION PLATE AND DETECTION SYSTEM COMBINED WITH PIEZOELECTRIC SENSING AND LOOP-MEDIATED ISOTHERMAL AMPLIFICATION, 授权时间2019-8-27, 美国, US 10392591B2
张威 研究员
研究方向：
电子邮件：zhangw@sibet.ac.cn
电 话：0512-69588061
通讯地址：苏州市高新区科技城科灵路88号